Overview
Clinical Meaning
TB management: LTBI treatment prevents progression to active TB (5 10% lifetime risk).
WHNP
WHNP
TB management: LTBI treatment prevents progression to active TB (5-10% lifetime risk). LTBI regimens: 3HP (isoniazid + rifapentine weekly x12 weeks, preferred), 4R (rifampin daily x4 months), 9H (isoniazid daily x9 months). Active TB: RIPE therapy (Rifampin, Isoniazid, Pyrazinamide, Ethambutol) x2 months intensive, then RI x4 months continuation. DOT (directly observed therapy) is standard of care. Isoniazid: supplement with pyridoxine (B6) 25-50mg to prevent peripheral neuropathy. Monitor LFTs monthly. Sputum AFB cultures at 2 months for conversion.
Unlock full lesson + practice questions
4 more sections with scenarios, priorities, and review drills.
Final rapid review before practice
Next study step
Finish the lesson first, then choose a focused activity to apply what you just reviewed.
Continue studying
Sign in to save progress on this lesson.
Unlock the interactive lesson quiz with a plan that includes this WHNP pathway. You can still explore topic-filtered questions from the bank hubs below.