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Hematology & Oncology Lessons
Canada pathway · 35 lessons
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Hematology & Oncology lessons — NCLEX-RN (NCLEX-RN) | NurseNest
Practice Exams
Lab values & correlations
Medication math
Skills refreshers
Pharmacology practice
Master telemetry through interactive ECG simulation
Prioritization & delegation
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Exam Overview
Hematology & Oncology Lessons
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35 lessons
Lesson
Neuroblastoma: RN Lesson
Neuroblastoma
Start
Osteosarcoma: RN Lesson
Osteosarcoma
Start
Acute Chest Syndrome in Sickle Cell Disease
Acute chest syndrome (ACS) is the leading cause of death and the second most common reason for hospitalization in patients with sickle cell disease (SCD).
Start
Acute Hemolytic Transfusion Reaction For
An acute hemolytic transfusion reaction (AHTR) is the most serious and potentially fatal complication of blood transfusion, occurring when pre-formed recipient antibodies (most commonly anti-A or anti-B isohemagglutinins) attack and rapidly destroy transfused donor red blood cells.
Start
Acute Lymphoblastic Leukemia
Acute lymphoblastic leukemia (ALL) results from malignant transformation of lymphoid progenitor cells in the bone marrow, producing clonal proliferation of immature lymphoblasts that crowd out normal hematopoietic cells, causing bone marrow failure.
Start
Acute Promyelocytic Leukemia (APL)
Acute promyelocytic leukemia (APL) is a distinct subtype of acute myeloid leukemia (AML-M3 in the FAB classification) characterized by the accumulation of abnormal promyelocytes in the bone marrow and a uniquely dangerous coagulopathy.
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Acute Radiation Pneumonitis
Radiation pneumonitis develops 1-6 months after thoracic irradiation when ionizing radiation damages type I and type II pneumocytes and pulmonary capillary endothelial cells.
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ALL and AML
Acute leukemias are clonal malignancies of hematopoietic progenitor cells characterized by uncontrolled proliferation of immature blast cells (>20% blasts in bone marrow) that crowd out normal hematopoiesis.
Start
Blood Transfusion: Administration
Blood transfusion reactions result from recipient immune response to foreign antigens on donor blood components.
Start
Budd-Chiari Syndrome
Budd-Chiari syndrome (BCS) refers to hepatic venous outflow obstruction occurring anywhere from the small hepatic venules to the junction of the inferior vena cava (IVC) with the right atrium, excluding obstruction caused by cardiac disease or sinusoidal obstruction syndrome (formerly known as…
Start
Chronic Lymphocytic Leukemia
Chronic lymphocytic leukemia (CLL) is the most common adult leukemia in Western countries, characterized by the clonal proliferation and progressive accumulation of functionally incompetent, mature-appearing CD5-positive B lymphocytes in the peripheral blood, bone marrow, lymph nodes, and spleen.
Start
Diffuse Alveolar Hemorrhage
Diffuse alveolar hemorrhage (DAH) is a life-threatening pulmonary emergency characterized by bleeding originating from the pulmonary microvasculature (alveolar capillaries, arterioles, and venules) into the alveolar spaces, producing the classic clinical triad of hemoptysis, diffuse bilateral…
Start
Esophageal Variceal Hemorrhage
Esophageal varices develop as a consequence of portal hypertension, most commonly from hepatic cirrhosis.
Start
Hairy Cell Leukemia
Hairy cell leukemia (HCL) is a rare, indolent B-cell lymphoproliferative disorder characterized by accumulation of mature B lymphocytes with distinctive cytoplasmic projections ('hairy' appearance) in the bone marrow, spleen, and peripheral blood.
Start
Hematologic Disorders
Hematopoiesis occurs primarily in the bone marrow, where pluripotent hematopoietic stem cells differentiate into all blood cell lineages through growth factor-mediated signaling — erythropoietin (EPO) from the kidneys drives red blood cell production, thrombopoietin (TPO) regulates platelet…
Start
Iron Deficiency Anemia
Iron deficiency anemia (IDA) develops through three progressive stages: (1) iron depletion—reduced ferritin stores with normal hemoglobin; (2) iron-deficient erythropoiesis—low serum iron, elevated TIBC, reduced transferrin saturation (<20%), with early microcytosis; (3) iron deficiency anemia—low…
Start
Liver Cirrhosis
Cirrhosis is the end-stage of chronic liver disease characterized by irreversible replacement of normal hepatic parenchyma with fibrous scar tissue and regenerative nodules.
Start
Neutropenic Precautions and Febrile Neutropenia
Neutropenia is defined as an absolute neutrophil count (ANC) below 1500/mm3, with severe neutropenia below 500/mm3 and profound neutropenia below 100/mm3.
Start
Oncology
Advanced oncology nursing requires understanding cancer at the cellular and molecular level, including the mechanisms of tumor growth, metastasis, and treatment resistance.
Start
Pericardial Mesothelioma
Pericardial mesothelioma is an extremely rare primary malignancy of the pericardial mesothelial lining, accounting for less than 1% of all mesotheliomas.
Start
Portal Vein Thrombosis
Portal vein thrombosis (PVT) involves partial or complete obstruction of the portal vein by thrombus, disrupting hepatic portal blood flow.
Start
Primary CNS Lymphoma
Primary CNS lymphoma (PCNSL) is a rare, aggressive non-Hodgkin lymphoma arising within the brain, spinal cord, leptomeninges, or eyes without systemic lymphoma involvement.
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Primary Sclerosing Cholangitis (PSC)
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease characterized by progressive inflammation, fibrosis, and stricturing of the intrahepatic and extrahepatic bile ducts, leading to bile duct obliteration, secondary biliary cirrhosis, and liver failure.
Start
Pulmonary Embolism Nursing: DVT, Wells Score, Anticoagulants and
Complete RN lesson on PE: Virchow's triad, Wells criteria, D-dimer, CTPA, heparin, thrombolytics, VTE prevention, and Canadian NCLEX-RN clinical priorities.
Start
Pulmonary Infarction
Pulmonary infarction occurs when a pulmonary embolism completely obstructs an end-artery, cutting off both pulmonary arterial and bronchial collateral blood supply to a segment of lung tissue.
Start
Pulmonary Langerhans Cell Histiocytosis
Pulmonary Langerhans cell histiocytosis (PLCH) is characterized by clonal proliferation of Langerhans cells (specialized dendritic cells bearing CD1a and CD207/langerin markers) that infiltrate the small airways and interstitium.
Start
Sickle Cell Disease
Sickle cell disease (SCD) is an autosomal recessive hemoglobinopathy caused by a single nucleotide substitution (GAG→GTG) in the beta-globin gene on chromosome 11, resulting in hemoglobin S (HbS) where valine replaces glutamic acid at position 6.
Start
Sickle Cell Vaso-Occlusive Crisis
In sickle cell disease, the valine-for-glutamic acid substitution at position 6 of the beta-globin chain produces hemoglobin S.
Start
Transfusion-Related Acute Lung Injury (TRALI)
TRALI is a non-cardiogenic pulmonary edema occurring within 6 hours of transfusion.
Start
Warm Autoimmune Hemolytic Anemia
Warm autoimmune hemolytic anemia (AIHA) is caused by IgG autoantibodies that bind red blood cells (RBCs) optimally at body temperature (37 degrees C), opsonizing them for destruction by splenic macrophages via Fc-receptor-mediated phagocytosis (extravascular hemolysis).
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Zollinger-Ellison Syndrome
Zollinger-Ellison syndrome (ZES) is caused by gastrin-secreting neuroendocrine tumors (gastrinomas) that produce massive, unregulated gastrin secretion, driving continuous maximal stimulation of parietal cell hydrogen-potassium ATPase pumps and causing gastric acid hypersecretion.
Start
Anticoagulants RN Clinical Readiness Admin Curated
NCLEX-RN RN admin-curated lesson for Anticoagulants, clinical reasoning, safety cues, and route-scoped practice.
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Antiseizure Medications RN Clinical Readiness Admin Curated
NCLEX-RN RN admin-curated lesson for Antiseizure Medications, clinical reasoning, safety cues, and route-scoped practice.
Start
Burkitt Lymphoma: Focused RN Companion
Burkitt Lymphoma: Focused RN Companion: canonical lesson for ca-rn-nclex-rn.
Start
Thrombolytics RN Clinical Readiness Admin Curated
NCLEX-RN RN admin-curated lesson for Thrombolytics, clinical reasoning, safety cues, and route-scoped practice.
Start
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